The effect of prolonged morphine administration on the in vivo and in vitro conjugation of morphine by rats.

I. The Biological Liberation of Morphine from Codeine in the Rat. T. K. Adler and F. H. Shaw 1 II. The Effect of Prolonged Morphine Administration on the In Vivo and In Vitro Conjugation of Morphine by Rats. Howard L. Zauder 11 III. Adenine Intoxication in Relation to In Vivo Formation and Deposition of 2,8-Dioxyadenine in Renal Tubules. Frederick S. Philips, John B. Thiersch and Aaron Bendich 20 IV. Renal Action of Mercurial Diuretics as Affected by Sodium Load. A. Farah, T. S. Cobbey, Jr. and W. Mook 31 V. Local Anesthetic Activity, Toxicity and Irritancy of 2-Alkoxy Analogs of Procaine and Tetracaine. F. P. Luduena and James 0. Hoppe 40 VI. Chronic Tolerance Studies on 9-Diethylaminoethyl Xanthene-9-Carboxylate Methobromide (Banthine). Homer B. Freese, W. E. Hambourger, Lyle D. Calvin and D. M. Green 54 VII. Chronic Oral Toxicity Tests of Methoxychlor (2, 2-Di-(P-Methoxyphenyl)1,1,1-Trichlorethane) in Rats and Dogs. Harold C. lodge, Elliott A. Maynard and H. J. Blanchet, Jr 60 VIII. Respiratory Effects of Potent Hypotensive Derivatives of Veratrum. Lois Mosey and A. Kaplan 67 IX. The Emetic Properties of Veratrum Derivatives. Edward D. Swiss 76 X. Prolongation of the Anticoagulant Action of Heparin with Procaine and Butacaine Conjugates. Ted A. Loomis, J. E. Jesseph and R. E. Beyer.. 87 XI. Metabolism of S3’ Thiopental (Pentothal). J. D. Taylor, R. K. Richards and D. L. Tabern 93 XII. Effects of Innervation and Drugs upon Direct Membrane Potentials of Embryonic Chick Myocardium. E. Fingi, L. A. Woodbury and H. H. Hecht 103